The S3 head is a 2 piece item. You have the anodized outer, and then the actual chamber insert. The outer is the same for both. If you buy the correct insert for the cylinder it will fit (ie 250 insert on a 250 cyl, or 300 insert on a 300 cylinder). The powervalve and spigot will fit in both cylinders too.
So if you have 2 cylinders, and an S3 head, all you need is the correct insert for each one. Make sense?